CATH Classification

Domain Context

CATH Clusters

Superfamily Glucose Permease (Domain IIA)
Functional Family

Enzyme Information

3.4.24.75
Lysostaphin.
based on mapping to UniProt O33599
Hydrolysis of the -Gly-|-Gly- bond in the pentaglycine inter-peptide link joining staphylococcal cell wall peptidoglycans.
-!- Lyses cells of Staphylococcus aureus in particular, by its action on the cross-bridge of the cell wall. -!- Belongs to peptidase family M23.

UniProtKB Entries (1)

O33599
LYTM_STAA8
Staphylococcus aureus subsp. aureus NCTC 8325
Glycyl-glycine endopeptidase LytM

PDB Structure

PDB 1QWY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Latent LytM at 1.3A resolution.
Odintsov, S.G., Sabala, I., Marcyjaniak, M., Bochtler, M.
J.Mol.Biol.