CATH Classification

Domain Context

CATH Clusters

Superfamily HAD superfamily/HAD-like
Functional Family

Enzyme Information

3.8.1.2
(S)-2-haloacid dehalogenase.
based on mapping to UniProt Q53464
(S)-2-haloacid + H(2)O = (R)-2-hydroxyacid + halide.
-!- Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 (see also EC 3.8.1.9, EC 3.8.1.10 and EC 3.8.1.11).

UniProtKB Entries (1)

Q53464
HAD_PSEUY
Pseudomonas sp. YL
(S)-2-haloacid dehalogenase

PDB Structure

PDB 1QH9
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Structure of L-2-Haloacid Dehalogenase Complexed with a Reaction Product Reveals the Mechanism of Intermediate Hydrolysis in Dehalogenase
Li, Y.-F., Hata, Y., Fujii, T., Kurihara, T., Esaki, N.
To be Published