CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Eukaryotic initiation factor 4A-II

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P10081
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P10081
IF4A_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase eIF4A

PDB Structure

PDB 1QDE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the ATPase domain of translation initiation factor 4A from Saccharomyces cerevisiae--the prototype of the DEAD box protein family.
Benz, J., Trachsel, H., Baumann, U.
Structure Fold.Des.