CATH Classification

Domain Context

CATH Clusters

Superfamily Chloramphenicol acetyltransferase-like domain
Functional Family Carnitine O-acetyltransferase

Enzyme Information

2.3.1.6
Choline O-acetyltransferase.
based on mapping to UniProt P32738
Acetyl-CoA + choline = CoA + O-acetylcholine.
-!- Propanoyl-CoA can act, more slowly, in place of acetyl-CoA.

UniProtKB Entries (1)

P32738
CLAT_RAT
Rattus norvegicus
Choline O-acetyltransferase

PDB Structure

PDB 1Q6X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders.
Cai, Y., Cronin, C.N., Engel, A.G., Ohno, K., Hersh, L.B., Rodgers, D.W.
Embo J.