CATH Classification

Domain Context

CATH Clusters

Superfamily PVUII Endonuclease, subunit A
Functional Family

Enzyme Information

3.1.21.4
Type II site-specific deoxyribonuclease.
based on mapping to UniProt P23657
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
-!- Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site. -!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/

UniProtKB Entries (1)

P23657
T2P2_PROHU
Proteus hauseri
Type-2 restriction enzyme PvuII

PDB Structure

PDB 1PVU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of PvuII endonuclease reveals extensive structural homologies to EcoRV.
Athanasiadis, A., Vlassi, M., Kotsifaki, D., Tucker, P.A., Wilson, K.S., Kokkinidis, M.
Nat.Struct.Biol.