CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.1670 | Endonuclease Iii, domain 2 |
|
1.10.1670.10 | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) |
Domain Context
CATH Clusters
| Superfamily | Helix-hairpin-Helix base-excision DNA repair enzymes (C-terminal) |
| Functional Family | DNA-3-methyladenine glycosylase 2 |
Enzyme Information
| 3.2.2.21 |
DNA-3-methyladenine glycosylase II.
based on mapping to UniProt P04395
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.
|
UniProtKB Entries (1)
| P04395 |
3MG2_ECOLI
Escherichia coli K-12
DNA-3-methyladenine glycosylase 2
|
PDB Structure
| PDB | 1PVS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
3-methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition.
Bioconjug.Chem.
|