CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.30 | Glutaredoxin |
|
3.40.30.10 | Glutaredoxin |
Domain Context
CATH Clusters
| Superfamily | Glutaredoxin |
| Functional Family | glutathione S-transferase 1 |
Enzyme Information
| 2.5.1.18 |
Glutathione transferase.
based on mapping to UniProt Q93113
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
|
| 4.5.1.1 |
DDT-dehydrochlorinase.
based on mapping to UniProt Q93113
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2- bis(4-chlorophenyl)ethylene + chloride.
|
UniProtKB Entries (1)
| Q93113 |
GST1D_ANOGA
Anopheles gambiae
Glutathione S-transferase 1, isoform D
|
PDB Structure
| PDB | 1PN9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae.
Acta Crystallogr.,Sect.D
|