CATH Classification

Domain Context

CATH Clusters

Superfamily DNA ligase/mRNA capping enzyme
Functional Family

Enzyme Information

2.7.7.50
mRNA guanylyltransferase.
based on mapping to UniProt P78587
GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA.
-!- Can modify also synthetic poly(A) and poly(G) to form the structures m(7)G(5')pppAn and m(7)G(5')pppGn.

UniProtKB Entries (1)

P78587
MCE1_CANAX
Candida albicans
MRNA-capping enzyme subunit alpha

PDB Structure

PDB 1P16
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II.
Fabrega, C., Shen, V., Shuman, S., Lima, C.D.
Mol.Cell