CATH Classification

Domain Context

CATH Clusters

Superfamily 2.20.28.60
Functional Family Citrate synthase

Enzyme Information

2.3.3.16
Citrate synthase (unknown stereospecificity).
based on mapping to UniProt P0ABH7
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
-!- This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).

UniProtKB Entries (1)

P0ABH7
CISY_ECOLI
Escherichia coli K-12
Citrate synthase

PDB Structure

PDB 1OWC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Probing the roles of key residues in the unique regulatory NADH binding site of type II citrate synthase of Escherichia coli.
Stokell, D.J., Donald, L.J., Maurus, R., Nguyen, N.T., Sadler, G., Choudhary, K., Hultin, P.G., Brayer, G.D., Duckworth, H.W.
J.Biol.Chem.