CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaconate Coenzyme A-transferase
Functional Family Succinyl-coa:3-ketoacid-coenzyme a transferase subunit b

Enzyme Information

2.8.3.5
3-oxoacid CoA-transferase.
based on mapping to UniProt Q29551
Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.
-!- Acetoacetate or, more slowly, 3-oxopropanoate, 3-oxopentanoate, 3-oxo-4-methylpentanoate or 3-oxohexanoate can act as acceptor. -!- Malonyl-CoA can act instead of succinyl-CoA.

UniProtKB Entries (1)

Q29551
SCOT1_PIG
Sus scrofa
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

PDB Structure

PDB 1OOY
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the CoA transferase from pig heart to 1.7 A resolution.
Coros, A.M., Swenson, L., Wolodko, W.T., Fraser, M.E.
Acta Crystallogr.,Sect.D