CATH Classification

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Nuclear receptor coactivator

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P70365
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (2)

P70365
NCOA1_MOUSE
Mus musculus
Nuclear receptor coactivator 1
P42226
STAT6_HUMAN
Homo sapiens
Signal transducer and activator of transcription 6

PDB Structure

PDB 1OJ5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Ncoa-1/Src-1 Pas-B Domain Bound to the Lxxll Motif of the Stat6 Transactivation Domain
Razeto, A., Ramakrishnan, V., Litterst, C.M., Giller, K., Griesinger, C., Carlomagno, T., Lakomek, N., Heimburg, T., Lodrini, M., Pfitzner, E., Becker, S.
J.Mol.Biol.