CATH Classification

Domain Context

CATH Clusters

Superfamily Ras guanine-nucleotide exchange factors catalytic domain
Functional Family son of sevenless homolog 1 isoform X2

Enzyme Information

UniProtKB Entries (1)

Q07889
SOS1_HUMAN
Homo sapiens
Son of sevenless homolog 1

PDB Structure

PDB 1NVX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS
Margarit, S.M., Sondermann, H., Hall, B.E., Nagar, B., Hoelz, A., Pirruccello, M., Bar-Sagi, D., Kuriyan, J.
Cell(Cambridge,Mass.)