CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.70 | Alpha-Beta Plaits |
|
3.30.70.141 | Nucleoside diphosphate kinase-like domain |
Domain Context
CATH Clusters
| Superfamily | Nucleoside diphosphate kinase-like domain |
| Functional Family | Nucleoside diphosphate kinase B |
Enzyme Information
| 2.7.4.6 |
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22392
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.
|
| 2.7.13.3 |
Histidine kinase.
based on mapping to UniProt P22392
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.
|
UniProtKB Entries (1)
| P22392 |
NDKB_HUMAN
Homo sapiens
Nucleoside diphosphate kinase B
|
PDB Structure
| PDB | 1NSK |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.
J.Mol.Biol.
|