CATH Classification

Domain Context

CATH Clusters

Superfamily Pantoate-beta-alanine ligase, C-terminal domain
Functional Family Pantothenate synthetase

Enzyme Information

6.3.2.1
Pantoate--beta-alanine ligase (AMP-forming).
based on mapping to UniProt P9WIL5
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.

UniProtKB Entries (1)

P9WIL5
PANC_MYCTU
Mycobacterium tuberculosis H37Rv
Pantothenate synthetase

PDB Structure

PDB 1N2H
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structures of a pantothenate synthetase from M. tuberculosis and its complexes with substrates and a reaction intermediate
Wang, S., Eisenberg, D.
Protein Sci.