CATH Classification

Domain Context

CATH Clusters

Superfamily SET domain
Functional Family Histone-lysine N-methyltransferase, H3 lysine-9 specific

Enzyme Information

2.1.1.43
Histone-lysine N-methyltransferase.
based on mapping to UniProt O60016
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].

UniProtKB Entries (1)

O60016
CLR4_SCHPO
Schizosaccharomyces pombe 972h-
Histone-lysine N-methyltransferase, H3 lysine-9 specific

PDB Structure

PDB 1MVX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure of the SET domain histone lysine methyltransferase Clr4.
Min, J., Zhang, X., Cheng, X., Grewal, S.I., Xu, R.M.
Nat.Struct.Biol.