CATH Classification

Domain Context

CATH Clusters

Superfamily SH3 Domains
Functional Family myc box-dependent-interacting protein 1 isoform X2

Enzyme Information

UniProtKB Entries (1)

O00499
BIN1_HUMAN
Homo sapiens
Myc box-dependent-interacting protein 1

PDB Structure

PDB 1MUZ
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants.
Pineda-Lucena, A., Ho, C.S., Mao, D.Y., Sheng, Y., Laister, R.C., Muhandiram, R., Lu, Y., Seet, B.T., Katz, S., Szyperski, T., Penn, L.Z., Arrowsmith, C.H.
J.Mol.Biol.