CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P00346
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P00346
MDHM_PIG
Sus scrofa
Malate dehydrogenase, mitochondrial

PDB Structure

PDB 1MLD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases.
Gleason, W.B., Fu, Z., Birktoft, J., Banaszak, L.
Biochemistry