CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.390.30
Functional Family Putative apoptosis-inducing factor 1, mitochondrial

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt O95831

UniProtKB Entries (1)

O95831
AIFM1_HUMAN
Homo sapiens
Apoptosis-inducing factor 1, mitochondrial

PDB Structure

PDB 1M6I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
DNA binding is required for the apoptogenic action of apoptosis inducing factor.
Ye, H., Cande, C., Stephanou, N.C., Jiang, S., Gurbuxani, S., Larochette, N., Daugas, E., Garrido, C., Kroemer, G., Wu, H.
Nat.Struct.Biol.