CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.530.40
Functional Family

Enzyme Information

3.2.1.17
Lysozyme.
based on mapping to UniProt P00720
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.
-!- Cf. EC 3.2.1.14.

UniProtKB Entries (1)

P00720
ENLYS_BPT4
Escherichia virus T4
Endolysin

PDB Structure

PDB 1LWK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Multiple methionine substitutions are tolerated in T4 lysozyme and have coupled effects on folding and stability.
Gassner, N.C., Baase, W.A., Mooers, B.H., Busam, R.D., Weaver, L.H., Lindstrom, J.D., Quillin, M.L., Matthews, B.W.
Biophys.Chem.