CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family Fructose-1,6-bisphosphatase class 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt P00636
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

P00636
F16P1_PIG
Sus scrofa
Fructose-1,6-bisphosphatase 1

PDB Structure

PDB 1LEV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site.
Wright, S.W., Carlo, A.A., Danley, D.E., Hageman, D.L., Karam, G.A., Mansour, M.N., McClure, L.D., Pandit, J., Schulte, G.K., Treadway, J.L., Wang, I.-K., Bauer, P.H.
Bioorg.Med.Chem.Lett.