CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1400
Functional Family Ferrochelatase

Enzyme Information

4.99.1.1
Protoporphyrin ferrochelatase.
based on mapping to UniProt P16622
Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
-!- The enzyme catalyzes the terminal step in the heme biosynthesis pathways of eukaryotes and Gram-negative bacteria.

UniProtKB Entries (1)

P16622
HEMH_YEAST
Saccharomyces cerevisiae S288C
Ferrochelatase, mitochondrial

PDB Structure

PDB 1L8X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Metal Binding to Saccharomyces cerevisiae Ferrochelatase
Karlberg, T., Lecerof, D., Gora, M., Silvegren, G., Labbe-Bois, R., Hansson, M., Al-Karadaghi, S.
Biochemistry