CATH Classification

Domain Context

CATH Clusters

Superfamily Protein tyrosine phosphatase superfamily
Functional Family Tyrosine-protein phosphatase non-receptor type 1

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P17706
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P17706
PTN2_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 2

PDB Structure

PDB 1L8K
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure determination of T cell protein-tyrosine phosphatase.
Iversen, L.F., Moller, K.B., Pedersen, A.K., Peters, G.H., Petersen, A.S., Andersen, H.S., Branner, S., Mortensen, S.B., Moller, N.P.
J.Biol.Chem.