CATH Classification

Domain Context

CATH Clusters

Superfamily Aldehyde Dehydrogenase; Chain A, domain 2
Functional Family NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.90
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)).
based on mapping to UniProt O57693
D-glyceraldehyde 3-phosphate + NAD(P)(+) + H(2)O = 3-phospho-D-glycerate + NAD(P)H.
-!- The enzyme is part of the modified Embden-Meyerhof-Parnas pathway of the archaeon Thermoproteus tenax (cf. EC 1.2.1.9).

UniProtKB Entries (1)

O57693
GAPN_THETE
Thermoproteus tenax
NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1KY8
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The Crystal Structure of the Allosteric Non-phosphorylating glyceraldehyde-3-phosphate Dehydrogenase from the Hyperthermophilic Archaeum Thermoproteus tenax
Pohl, E., Brunner, N., Wilmanns, M., Hensel, R.
J.Biol.Chem.