CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family dTDP-glucose 4,6-dehydratase

Enzyme Information

4.2.1.46
dTDP-glucose 4,6-dehydratase.
based on mapping to UniProt P26391
dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.

UniProtKB Entries (1)

P26391
RMLB_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
DTDP-glucose 4,6-dehydratase

PDB Structure

PDB 1KEW
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Toward a structural understanding of the dehydratase mechanism.
Allard, S.T., Beis, K., Giraud, M.F., Hegeman, A.D., Gross, J.W., Wilmouth, R.C., Whitfield, C., Graninger, M., Messner, P., Allen, A.G., Maskell, D.J., Naismith, J.H.
Structure