CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Anionic trypsin-2

Enzyme Information

3.4.21.4
Trypsin.
based on mapping to UniProt P00763
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

P00763
TRY2_RAT
Rattus norvegicus
Anionic trypsin-2
P14754
SERA_MANSE
Manduca sexta
Alaserpin

PDB Structure

PDB 1K9O
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The structure of a Michaelis serpin-protease complex.
Ye, S., Cech, A.L., Belmares, R., Bergstrom, R.C., Tong, Y., Corey, D.R., Kanost, M.R., Goldsmith, E.J.
Nat.Struct.Biol.