CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family DNA polymerase III subunit delta

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P28630
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P28630
HOLA_ECOLI
Escherichia coli K-12
DNA polymerase III subunit delta

PDB Structure

PDB 1JQJ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III.
Jeruzalmi, D., Yurieva, O., Zhao, Y., Young, M., Stewart, J., Hingorani, M., O'Donnell, M., Kuriyan, J.
Cell(Cambridge,Mass.)