CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P36873
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P36873
PP1G_HUMAN
Homo sapiens
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

PDB Structure

PDB 1JK7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the tumor-promoter okadaic acid bound to protein phosphatase-1.
Maynes, J.T., Bateman, K.S., Cherney, M.M., Das, A.K., Luu, H.A., Holmes, C.F., James, M.N.
J.Biol.Chem.