CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
| Superfamily | Vaccinia Virus protein VP39 |
| Functional Family | Protein-L-isoaspartate O-methyltransferase |
Enzyme Information
| 2.1.1.77 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase.
based on mapping to UniProt Q8TZR3
S-adenosyl-L-methionine + protein L-isoaspartate = S-adenosyl-L- homocysteine + protein L-isoaspartate alpha-methyl ester.
-!- D-aspartate (but not L-aspartate) residues in proteins can also act as acceptors. -!- Formerly EC 2.1.1.24.
|
UniProtKB Entries (1)
| Q8TZR3 |
PIMT_PYRFU
Pyrococcus furiosus DSM 3638
Protein-L-isoaspartate O-methyltransferase
|
PDB Structure
| PDB | 1JG1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate.
J.Mol.Biol.
|