CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family DNA polymerase III subunit epsilon

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P03007
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P03007
DPO3E_ECOLI
Escherichia coli K-12
DNA polymerase III subunit epsilon

PDB Structure

PDB 1J53
External Links
Method X-RAY DIFFRACTION
Organism T7-like viruses
Primary Citation
Structural Basis for Proofreading during Replication of the Escherichia coli Chromosome
Hamdan, S., Carr, P.D., Brown, S.E., Ollis, D.L., Dixon, N.E.
Structure