CATH Classification

Domain Context

CATH Clusters

Superfamily Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family Insulin receptor substrate 1

Enzyme Information

UniProtKB Entries (1)

P24394
IL4RA_HUMAN
Homo sapiens
Interleukin-4 receptor subunit alpha

PDB Structure

PDB 1IRS
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.
Zhou, M.M., Huang, B., Olejniczak, E.T., Meadows, R.P., Shuker, S.B., Miyazaki, M., Trub, T., Shoelson, S.E., Fesik, S.W.
Nat.Struct.Biol.