CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Isoleucine--tRNA ligase

Enzyme Information

6.1.1.5
Isoleucine--tRNA ligase.
based on mapping to UniProt P56690
ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile).

UniProtKB Entries (1)

P56690
SYI_THET8
Thermus thermophilus HB8
Isoleucine--tRNA ligase

PDB Structure

PDB 1ILE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Enzyme structure with two catalytic sites for double-sieve selection of substrate.
Nureki, O., Vassylyev, D.G., Tateno, M., Shimada, A., Nakama, T., Fukai, S., Konno, M., Hendrickson, T.L., Schimmel, P., Yokoyama, S.
Science