CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Member RAS oncogene family

Enzyme Information

UniProtKB Entries (1)

P35278
RAB5C_MOUSE
Mus musculus
Ras-related protein Rab-5C

PDB Structure

PDB 1HUQ
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Merithew, E., Hatherly, S., Dumas, J.J., Lawe, D.C., Heller-Harrison, R., Lambright, D.G.
J.Biol.Chem.