CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | Glutamate dehydrogenase |
Enzyme Information
| 1.4.1.2 |
Glutamate dehydrogenase.
based on mapping to UniProt P24295
L-glutamate + H(2)O + NAD(+) = 2-oxoglutarate + NH(3) + NADH.
|
UniProtKB Entries (1)
| P24295 |
DHE2_CLOSY
[Clostridium] symbiosum
NAD-specific glutamate dehydrogenase
|
PDB Structure
| PDB | 1HRD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structure of Pyrococcus furiosus glutamate dehydrogenase reveals a key role for ion-pair networks in maintaining enzyme stability at extreme temperatures.
Structure
|