CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P05102
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (1)

P05102
MTH1_HAEPH
Haemophilus parahaemolyticus
Modification methylase HhaI

PDB Structure

PDB 1HMY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.
Cheng, X., Kumar, S., Posfai, J., Pflugrath, J.W., Roberts, R.J.
Cell(Cambridge,Mass.)