CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.8.1.5
Haloalkane dehalogenase.
based on mapping to UniProt P22643
1-haloalkane + H(2)O = a primary alcohol + halide.
-!- Acts on a wide range of 1-haloalkanes, haloalcohols, haloalkenes and some haloaromatic compounds.

UniProtKB Entries (1)

P22643
DHLA_XANAU
Xanthobacter autotrophicus
Haloalkane dehalogenase

PDB Structure

PDB 1HDE
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range.
Schanstra, J.P., Ridder, I.S., Heimeriks, G.J., Rink, R., Poelarends, G.J., Kalk, K.H., Dijkstra, B.W., Janssen, D.B.
Biochemistry