CATH Classification

Domain Context

CATH Clusters

Superfamily Chorismate lyase-like
Functional Family Chorismate pyruvate-lyase

Enzyme Information

4.1.3.40
Chorismate lyase.
based on mapping to UniProt P26602
Chorismate = 4-hydroxybenzoate + pyruvate.
-!- Catalyzes the first step in the biosynthesis of ubiquinone in Escherichia coli and other Gram-negative bacteria. -!- The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine.

UniProtKB Entries (1)

P26602
UBIC_ECOLI
Escherichia coli K-12
Chorismate pyruvate-lyase

PDB Structure

PDB 1G81
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
The crystal structure of chorismate lyase shows a new fold and a tightly retained product.
Gallagher, D.T., Mayhew, M., Holden, M.J., Howard, A., Kim, K.J., Vilker, V.L.
Proteins