CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.90 | Alpha-Beta Complex |
|
3.90.190 | Protein-Tyrosine Phosphatase; Chain A |
|
3.90.190.10 | Protein tyrosine phosphatase superfamily |
Domain Context
CATH Clusters
| Superfamily | Protein tyrosine phosphatase superfamily |
| Functional Family |
Enzyme Information
| 3.1.3.48 |
Protein-tyrosine-phosphatase.
based on mapping to UniProt P74873
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.
|
UniProtKB Entries (2)
| P63000 |
RAC1_HUMAN
Homo sapiens
Ras-related C3 botulinum toxin substrate 1
|
| P74873 |
SPTP_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Secreted effector protein SptP
|
PDB Structure
| PDB | 1G4U |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1.
Mol.Cell
|