CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family Ribonuclease H

Enzyme Information

3.1.26.4
Ribonuclease H.
based on mapping to UniProt P0A7Y4
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.

UniProtKB Entries (1)

P0A7Y4
RNH_ECOLI
Escherichia coli K-12
Ribonuclease HI

PDB Structure

PDB 1G15
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Co-crystal of Escherichia coli RNase HI with Mn2+ ions reveals two divalent metals bound in the active site.
Goedken, E.R., Marqusee, S.
J.Biol.Chem.