CATH Classification

CATH Clusters

Superfamily Alpha carbonic anhydrase
Functional Family Alpha carbonic anhydrase 3

Enzyme Information

4.2.1.1
Carbonic anhydrase.
based on mapping to UniProt P00918
H(2)CO(3) = CO(2) + H(2)O.
-!- The enzyme catalyzes the reversible hydration of gaseous CO(2) to carbonic acid, which spontaneously converts to hydrogencarbonate under neutral pH. -!- It is widespread and found in archaea, bacteria, and eukaryotes. -!- Three distinct classes exist, and appear to have evolved independently.

UniProtKB Entries (1)

P00918
CAH2_HUMAN
Homo sapiens
Carbonic anhydrase 2

PDB Structure

PDB 1G0E
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and kinetic analysis of the chemical rescue of the proton transfer function of carbonic anhydrase II.
Duda, D., Tu, C., Qian, M., Laipis, P., Agbandje-McKenna, M., Silverman, D.N., McKenna, R.
Biochemistry