CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate/ornithine carbamoyltransferase
Functional Family Ornithine carbamoyltransferase, mitochondrial

Enzyme Information

2.1.3.3
Ornithine carbamoyltransferase.
based on mapping to UniProt P84010
Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
-!- The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively.

UniProtKB Entries (1)

P84010
OTC_SHEEP
Ovis aries
Ornithine carbamoyltransferase, mitochondrial

PDB Structure

PDB 1FB5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional and structural characterization of ovine ornithine transcarbamoylase.
De Gregorio, A., Battistutta, R., Arena, N., Panzalorto, M., Francescato, P., Valentini, G., Bruno, G., Zanotti, G.
Org.Biomol.Chem.