CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P45481
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P45481
CBP_MOUSE
Mus musculus
CREB-binding protein

PDB Structure

PDB 1F81
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution structure of the TAZ2 (CH3) domain of the transcriptional adaptor protein CBP.
De Guzman, R.N., Liu, H.Y., Martinez-Yamout, M., Dyson, H.J., Wright, P.E.
J.Mol.Biol.