CATH Classification

Domain Context

CATH Clusters

Superfamily PK beta-barrel domain-like
Functional Family

Enzyme Information

2.7.1.40
Pyruvate kinase.
based on mapping to UniProt P11974
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).

UniProtKB Entries (1)

P11974
KPYM_RABIT
Oryctolagus cuniculus
Pyruvate kinase PKM

PDB Structure

PDB 1F3X
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural and functional linkages between subunit interfaces in mammalian pyruvate kinase.
Wooll, J.O., Friesen, R.H., White, M.A., Watowich, S.J., Fox, R.O., Lee, J.C., Czerwinski, E.W.
J.Mol.Biol.