CATH Classification

Domain Context

CATH Clusters

Superfamily Lyase 2-enoyl-coa Hydratase, Chain A, domain 2
Functional Family Probable enoyl-CoA hydratase, mitochondrial

Enzyme Information

4.2.1.17
Enoyl-CoA hydratase.
based on mapping to UniProt P14604
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
-!- Acts in the reverse direction. -!- With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).

UniProtKB Entries (1)

P14604
ECHM_RAT
Rattus norvegicus
Enoyl-CoA hydratase, mitochondrial

PDB Structure

PDB 1EY3
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion.
Bahnson, B.J., Anderson, V.E., Petsko, G.A.
Biochemistry