CATH Classification

CATH Clusters

Superfamily ATP-grasp fold, B domain
Functional Family D-alanine--D-alanine ligase

Enzyme Information

6.3.2.4
D-alanine--D-alanine ligase.
based on mapping to UniProt Q03ZI1
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.

UniProtKB Entries (1)

Q03ZI1
DDL_LEUMM
Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
D-alanine--D-alanine ligase

PDB Structure

PDB 1EHI
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Enzymes of vancomycin resistance: the structure of D-alanine-D-lactate ligase of naturally resistant Leuconostoc mesenteroides.
Kuzin, A.P., Sun, T., Jorczak-Baillass, J., Healy, V.L., Walsh, C.T., Knox, J.R.
Structure Fold.Des.