CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Arylsulfatase A

Enzyme Information

3.1.6.8
Cerebroside-sulfatase.
based on mapping to UniProt P15289
A cerebroside 3-sulfate + H(2)O = a cerebroside + sulfate.
-!- Hydrolyzes galactose-3-sulfate residues in a number of lipids. -!- Also hydrolyzes ascorbate 2-sulfate and many phenol sulfates.

UniProtKB Entries (1)

P15289
ARSA_HUMAN
Homo sapiens
Arylsulfatase A

PDB Structure

PDB 1E1Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.
von Bulow, R., Schmidt, B., Dierks, T., von Figura, K., Uson, I.
J. Mol. Biol.