CATH Classification

Domain Context

CATH Clusters

Superfamily CRIB domain
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P35465
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (2)

P35465
PAK1_RAT
Rattus norvegicus
Serine/threonine-protein kinase PAK 1
P60953
CDC42_HUMAN
Homo sapiens
Cell division control protein 42 homolog

PDB Structure

PDB 1E0A
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution Structure of Cdc42 Bound to the Gtpase Binding Domian of Pak
Morreale, A., Venkatesan, M., Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Laue, E.D.
Nat.Struct.Biol.