CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Carboxypeptidase A1

Enzyme Information

3.4.17.15
Carboxypeptidase A2.
based on mapping to UniProt P48052
Similar to that of carboxypeptidase A (EC 3.4.17.1), but with a preference for bulkier C-terminal residues.
-!- Isolated from rat pancreas but not present in cattle pancreas. -!- Belongs to peptidase family M14.

UniProtKB Entries (2)

P48052
CBPA2_HUMAN
Homo sapiens
Carboxypeptidase A2
P81511
MCPI_HIRME
Hirudo medicinalis
Metallocarboxypeptidase inhibitor

PDB Structure

PDB 1DTD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of a novel leech carboxypeptidase inhibitor determined free in solution and in complex with human carboxypeptidase A2.
Reverter, D., Fernandez-Catalan, C., Baumgartner, R., Pfander, R., Huber, R., Bode, W., Vendrell, J., Holak, T.A., Aviles, F.X.
Nat.Struct.Biol.