CATH Classification

Domain Context

CATH Clusters

Superfamily Dihydrodipicolinate Reductase; domain 2
Functional Family Glyceraldehyde-3-phosphate dehydrogenase

Enzyme Information

1.2.1.12
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating).
based on mapping to UniProt P00362
D-glyceraldehyde 3-phosphate + phosphate + NAD(+) = 3-phospho-D-glyceroyl phosphate + NADH.
-!- Also acts very slowly on D-glyceraldehyde and some other aldehydes. -!- Thiols can replace phosphate.

UniProtKB Entries (1)

P00362
G3P_GEOSE
Geobacillus stearothermophilus
Glyceraldehyde-3-phosphate dehydrogenase

PDB Structure

PDB 1DBV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A crystallographic comparison between mutated glyceraldehyde-3-phosphate dehydrogenases from Bacillus stearothermophilus complexed with either NAD+ or NADP+.
Didierjean, C., Rahuel-Clermont, S., Vitoux, B., Dideberg, O., Branlant, G., Aubry, A.
J.Mol.Biol.