CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent dethiobiotin synthetase BioD

Enzyme Information

6.3.3.3
Dethiobiotin synthase.
based on mapping to UniProt P13000
ATP + 7,8-diaminononanoate + CO(2) = ADP + phosphate + dethiobiotin.
-!- CTP has half the activity of ATP.

UniProtKB Entries (1)

P13000
BIOD1_ECOLI
Escherichia coli K-12
ATP-dependent dethiobiotin synthetase BioD 1

PDB Structure

PDB 1DAM
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis.
Kack, H., Sandmark, J., Gibson, K.J., Schneider, G., Lindqvist, Y.
Protein Sci.