CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Tyrosine-protein phosphatase non-receptor type 13

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q12923
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q12923
PTN13_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 13

PDB Structure

PDB 1D5G
External Links
Method SOLUTION NMR
Organism Escherichia
Primary Citation
Solution Structure of the PDZ2 Domain from Cytosolic Human Phosphatase hPTP1E Complexed with a Peptide Reveals Contribution of the beta2-beta3 Loop to PDZ Domain-Ligand Interactions
Kozlov, G., Banville, D., Gehring, K., Ekiel, I.
J.Mol.Biol.